SB202190 (RMML-00120891)
Cat. No.: RMML-00120891
Category: Inhibitors & Activators
INQUIRY
1 mg
5 mg
SB202190 is a selective, potent, cell-permeable inhibitor of p38 MAP kinases, inhibiting p38α. As a pyridinyl imidazole inhibitor, SB202190 directly binds p38 MAP kinases in the ATP binding pocket. LImproves the self-renewal ability of neural stem cells from NPC1-deficient mice. Blocks adiponectin-mediated proliferation of hematopoietic stem cells. Reduces BMP3-mediated proliferation of C3H10T1/2 mesenchymal stem cells. Induces cardiomyocyte differentiation from human embryonic stem cells.
Product Features
| Purity | ≥ 98% |
|---|---|
| Applications | Differentiation, Expansion, Maintenance |
| Cross Reactivity | Human, Mouse, Non-Human Primate, Other, Rat |
Compound Information
| Target Pathways | p38 MAPK |
|---|---|
| CAS Number | 152121-30-7 |
| Molecular Formula | C₂₀H₁₄FN₃O |
Storage & Shipping
| Handling | Refer to SDS for further information. |
|---|
For research use only. Not for clinical use.
