Human PCSK9 Matched Antibody Pair Kit (RMAB-0252019)
Cat. No.: RMAB-0252019
Category: Antibody Pair
INQUIRY
5 x 96 tests
Human PCSK9 Matched Antibody Pair Kits include a capture and a biotinylated detector antibody pair, along with a calibrated protein standard, suitable for sandwich ELISA. The Matched Antibody Pair Kit can be used to quantify native and recombinant human PCSK9._x000D_
Product Features
| Species Reactivity | Human |
|---|---|
| Range | 250 pg/mL - 16000 pg/mL |
| Sensitivity | 37.07 pg/mL |
| Applications | ELISA, IA |
| Key Features | Unlabeled capture antibody, biotin-labeled detection antibody and calibrated protein standard; For economical ELISA and ELISA-based assay development; Reacts with: Human; Range: 250 pg/mL - 16000 pg/mL |
Target Information
| Target Symbol | PCSK9 |
|---|---|
| Target Name | Proprotein convertase subtilisin/kexin type 9 |
| UniProt ID | Q8NBP7 |
| Cellular Localization | Secreted. |
| Function | May be implicated in the differentiation of cortical neurons and may play a role in cholesterol homeostasis. |
| Involvement in Disease | Defects in PCSK9 are the cause of familial hypercholesterolemia 3 (FH3). FH3 inheritance is autosomal dominant. |
| Post-translational Modifications | The soluble zymogen undergoes autocatalytic intramolecular processing in the endoplasmic reticulum, resulting in the cleavage of its propeptide that remains associated with the secreted enzyme. |
| Sequence Similarities | Belongs to the peptidase S8 family. Contains 1 peptidase S8 domain. |
Storage & Shipping
| Storage & Shipping | Store at -20°C. Please refer to protocols. |
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For research use only. Not for clinical use.
