Human Recombinant TGF-alpha (RMPP-00231603)
Cat. No.: RMPP-00231603
Category: Recombinant Protein
Research Area: Epithelial Cell Biology
INQUIRY
1 mg
5 mg
Transforming growth factor-alpha (TGF-α) a member of the epidermal growth factor (EGF) family that is expressed in normal epithelial cells, monocytes, macrophages, brain cells, keratinocytes, and cancer cells. TGF-α binds EGF receptor (EGFR) and activates tyrosine kinase signaling. In epidermal and epithelial cells, this results in proliferation and differentiation. TGF-α is not structurally or genetically related to TGF-β, and the two ligands act thro μgh different signaling pathways. In vitro, TGF-α was shown to stimulate anchorage-independent growth (Singh & Coffey).
Product Features
| Purity | ≥ 95% |
|---|---|
| Nature | Recombinant |
| Cross Reactivity | Human |
Storage & Shipping
| Shipping and Storage | Shipped on Dry Ice. |
|---|
For research use only. Not for clinical use.
