IDE 1, endoderm formation inducer (RMML-00120745)
Cat. No.: RMML-00120745
Category: Inhibitors & Activators
INQUIRY
1 mg
Potent cell-permeable definitive endoderm formation inducer
Product Features
| Source | Synthetic |
|---|---|
| Purity | > 99% |
| Key Features | Potent cell-permeable definitive endoderm formation inducer; CAS Number: 1160927-48-9; Purity: > 99%; Soluble in DMSO to 75 mM and in ethanol to 25 mM (with warming); Form / State: Solid; Source: Synthetic |
Compound Information
| Biological Description | Potent cell-permeable definitive endoderm formation inducer (EC50 = 125 nM, ESC) similar to IDE 2 (ab145223). Induces Sox17 expression. Activates TGF-β signaling and downstream Smad2 phosphorylation. Upregulates Nodal expression. Induces gut tube formation in vivo. |
|---|---|
| CAS Number | 1160927-48-9 |
| Chemical Name | 7-[2-(2-Carboxybenzylidene)hydrazinyl]-7-oxoheptanoic acid |
| SMILES | OC(=O)c1ccccc1/C=N/NC(=O)CCCCCC(=O)O |
| Molecular Formula | C15H18N2O5 |
| Molecular Weight | 306.30 Da |
Storage & Shipping
| Handling | Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. |
|---|---|
| Solubility | Soluble in DMSO to 75 mM and in ethanol to 25 mM (with warming) |
| Storage & Shipping | Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. |
For research use only. Not for clinical use.
