KD5170, HDAC inhibitor (RMML-00120791)
Cat. No.: RMML-00120791
Category: Inhibitors & Activators
INQUIRY
10 mg
Potent, non-selective HDAC inhibitor. Antiproliferative agent.
Product Features
| Source | Synthetic |
|---|---|
| Purity | > 95% |
| Key Features | Potent, non-selective HDAC inhibitor. Antiproliferative agent.; CAS Number: 940943-37-3; Purity: > 95%; Soluble in DMSO to 100 mM and in 1eq. HCl to 100 mM; Form / State: Solid; Source: Synthetic |
Compound Information
| Target Pathways | HDAC |
|---|---|
| Biological Description | Potent, non-selective HDAC inhibitor (IC50 values are 14, 20, 26 and 75 nM for HDAC6, 1, 4, and 3, respectively and 2 μM for HDAC2). Antiproliferative agent. Induces oxidative stress and oxidative DNA damage. Shows antitumor effects in vivo. Orally active. |
| CAS Number | 940943-37-3 |
| Chemical Name | S-[2-[6-[[4-[3-(Dimethylamino)propoxy]phenyl]sulfonylamino]-3-pyridinyl]-2-oxoethyl] ethanethioic acid ester |
| SMILES | CC(=O)SCC(=O)C1=CN=C(C=C1)NS(=O)(=O)C2=CC=C(C=C2)OCCCN(C)C |
| Molecular Formula | C20H25N3O5S2 |
| Molecular Weight | 451.55 Da |
| PubChem Identifier | 17754557 |
Storage & Shipping
| Handling | Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. |
|---|---|
| Solubility | Soluble in DMSO to 100 mM and in 1eq. HCl to 100 mM |
| Storage & Shipping | Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. |
For research use only. Not for clinical use.
