Suberoyl bis-hydroxamic acid (SBHA), HDAC inhibitor (RMML-00120790)
Cat. No.: RMML-00120790
Category: Inhibitors & Activators
INQUIRY
500 mg
100 mg
Potent, non-selective HDAC inhibitor
Product Features
| Source | Synthetic |
|---|---|
| Purity | > 98% |
| Key Features | Potent, non-selective HDAC inhibitor; CAS Number: 38937-66-5; Purity: > 98%; Soluble in water to 100 mM and in DMSO to 100 mM; Form / State: Solid; Source: Synthetic |
Compound Information
| Target Pathways | HDAC |
|---|---|
| Biological Description | Potent, non-selective HDAC inhibitor (ID50 values are 0.25 and 0.3 μM for HDAC1 and HDAC3 respectively). Potentiates the cytostatic effects of 5-Fluorouracil (ab142387). Induces apoptosis. Shows antiproliferative effects (IC50 = 15 μM, HeLa cells). |
| CAS Number | 38937-66-5 |
| Chemical Name | N,N′-Dihydroxyoctanediamide |
| SMILES | C(CCCC(=O)NO)CCC(=O)NO |
| Molecular Formula | C8H16N2O4 |
| Molecular Weight | 204.23 Da |
| PubChem Identifier | 5173 |
Storage & Shipping
| Handling | Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. |
|---|---|
| Solubility | Soluble in water to 100 mM and in DMSO to 100 mM |
| Storage & Shipping | Store at room temperature. The product can be stored for up to 12 months. |
For research use only. Not for clinical use.
