Kenpaullone (RMML-00120580)
Cat. No.: RMML-00120580
Category: Inhibitors & Activators
INQUIRY
1 mg
5 mg
Kenpaullone is an ATP-competitive inhibitor of glycogen synthase kinase 3β. It inhibits GSK-3β, Cdk1/cyclin B, Cdk2/cyclin A, Cdk5/p25, and lymphocyte kinase with IC₅₀ values of 0. 23, 0. 4, 0. 68, 0. 85, and 0. 47 µM, respectively. Replaces Klf4 in the generation of induced pluripotent stem. Enhances neuronal differentiation in rat and human neural precursor cell cultures. Promotes survival of motor neurons derived from mouse embryonic stem. Inhibits KLF4 expression and self-renewal in breast cancer stem cells in vitro.
Product Features
| Purity | ≥ 98% |
|---|---|
| Applications | Differentiation, Reprogramming |
| Cross Reactivity | Human, Mouse, Non-Human Primate, Other, Rat |
Compound Information
| Target Pathways | WNT |
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| CAS Number | 142273-20-9 |
| Molecular Formula | C₁₆H₁₁BrN₂O |
Storage & Shipping
| Handling | Refer to SDS for further information. |
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For research use only. Not for clinical use.
