Mitoxantrone dihydrochloride, Type II topoisomerase inhibitor (RMML-00121073)
Cat. No.: RMML-00121073
Category: Inhibitors & Activators
INQUIRY
50 mg
Type II topoisomerase inhibitor
Product Features
| Source | Synthetic |
|---|---|
| Purity | > 98% |
| Key Features | Type II topoisomerase inhibitor; CAS Number: 70476-82-3; Purity: > 98%; Soluble in DMSO to 100 mM and in water to 10 mM; Form / State: Solid; Source: Synthetic |
Compound Information
| Target Pathways | Type II topoisomerase |
|---|---|
| Biological Description | Type II topoisomerase inhibitor (IC50 = 50 nM). Able to inhibit DNA and protein synthesis, and induce both DNA strand breakage and cross linkage. Antineoplastic, immunomodulatory and chemotherapeutic action. |
| CAS Number | 70476-82-3 |
| Chemical Name | 1,4-Dihydroxy-5,8-bis[[2-[(2-hydroxyethyl)amino]ethyl]amino]-9,10-anthracenedione dihydrochloride |
| SMILES | Cl.Cl.OCCNCCNc3ccc(NCCNCCO)c2C(=O)c1c(O)ccc(O)c1C(=O)c23 |
| Molecular Formula | C22H28N4O6.2HCl |
| Molecular Weight | 517.41 Da |
| PubChem Identifier | 51082 |
Storage & Shipping
| Handling | Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Toxic, refer to SDS for further information. |
|---|---|
| Solubility | Soluble in DMSO to 100 mM and in water to 10 mM |
| Storage & Shipping | Store at room temperature. Store under desiccating conditions. The product can be stored for up to 12 months. |
For research use only. Not for clinical use.
