Murine GM-CSF Standard ABTS ELISA Development Kit (RMEK-0154048)
Cat. No.: RMEK-0154048
Category: ELISA Kits
INQUIRY
1 x 96 tests
Murine GM-CSF ELISA development kit contains the key components required for the quantitative measurement of natural and/or recombinant murine GM-CSF in a sandwich ELISA format. Using the ELISA protocol, the recommended microplates, reagents and solutions, the components supplied in this kit are sufficient to assay murine GM-CSF approximately 1000 ELISA plate wells.
Product Features
| Species Reactivity | Murine |
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Target Information
| Target Symbol | GMCSF |
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| UniProt ID | P04141 |
| Function | Low affinity receptor for granulocyte-macrophage colony-stimulating factor. Transduces a signal that results in the proliferation, differentiation, and functional activation of hematopoietic cells. |
| Cellular Localization | Secreted and Cell membrane. |
| Domain | The WSXWS motif appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding.The box 1 motif is required for JAK interaction and/or activation. |
| Involvement in Disease | Defects in CSF2RA are the cause of pulmonary surfactant metabolism dysfunction type 4 (SMDP4). A rare lung disorder due to impaired surfactant homeostasis. It is characterized by alveolar filling with floccular material that stains positive using the periodic acid-Schiff method and is derived from surfactant phospholipids and protein components. Excessive lipoproteins accumulation in the alveoli results in severe respiratory distress. |
Storage & Shipping
| Storage | Store at 2-8°C |
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| Shipping | Gel Packs |
| Stability | The stability of kit is determined by the loss rate of activity. The loss rate of this kit is less than 5% within the expiration date under appropriate storage condition. |
For research use only. Not for clinical use.
