NCH 51, HDAC inhibitor (RMML-00120668)
Cat. No.: RMML-00120668
Category: Inhibitors & Activators
INQUIRY
50 mg
10 mg
Novel HDAC inhibitor
Product Features
| Source | Synthetic |
|---|---|
| Purity | > 99% |
| Key Features | Novel HDAC inhibitor; CAS Number: 848354-66-5; Purity: > 99%; Soluble in DMSO to 100 mM and in ethanol to 25 mM; Form / State: Solid; Source: Synthetic |
Compound Information
| Target Pathways | HDAC |
|---|---|
| Biological Description | Novel HDAC inhibitor (IC50 values are 32, 48 and 41 nM at HDAC4, HDAC1 and HDAC6, respectively). Induces apoptosis and inhibits cell growth of various malignant cells and tumor cells lines (EC50 = 3.8 μM). Also reactivates latent HIV-1 gene expression. |
| Alternative Names | PTACH |
| CAS Number | 848354-66-5 |
| Chemical Name | 2-Methylpropanethioic acid S-[7-oxo-7-[(4-phenyl-2-thiazolyl)amino]heptyl] ester |
| SMILES | O=C(Nc1nc(cs1)c2ccccc2)CCCCCCSC(=O)C(C)C |
| Molecular Formula | C20H26N2O2S2 |
| Molecular Weight | 390.56 Da |
| PubChem Identifier | 11395181 |
Storage & Shipping
| Handling | Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Refer to SDS for further information. |
|---|---|
| Solubility | Soluble in DMSO to 100 mM and in ethanol to 25 mM |
| Storage & Shipping | Store at 4°C. The product can be stored for up to 12 months. |
For research use only. Not for clinical use.
