Nocodazole (RMML-00120658)
Cat. No.: RMML-00120658
Category: Inhibitors & Activators
INQUIRY
1 mg
5 mg
Nocodazole is an anti-mitotic agent that reversibly interferes with the polymerization of microtubules. Nocodazole binds to beta-tubulin and disrupts microtubule assembly/disassembly dynamics, impairing formation of the metaphase spindles during the cell division cycle. This prevents mitosis by inducing a G2/M-phase arrest and induces apoptosis in tumor cells. Synchronizes human pluripotent stem cells. Induces apoptosis in leukemic cells without harming T cells and/or mesenchymal stromal cells that were recovered from the same patients.
Product Features
| Purity | ≥ 98% |
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| Applications | Genome Editing |
| Cross Reactivity | Human, Mouse, Non-Human Primate, Other, Rat |
Compound Information
| CAS Number | 31430-18-9 |
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| Molecular Formula | C₁₄H₁₁N₃O₃S |
Storage & Shipping
| Handling | Refer to SDS for further information. |
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For research use only. Not for clinical use.
