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Organoid Growth Medium (Mouse Hepatic Progenitor)

Organoid Growth Medium (Mouse Hepatic Progenitor) (RMMS-00560065)

Cat. No.: RMMS-00560065

Category: Organoid Growth

Research Area: Cancer, Disease Modeling, Drug Discovery and Toxicity Testing, Epithelial Cell Biology, Stem Cell Biology

INQUIRY 1 Kit
Cell culture medium for establishment and maintenance of mouse hepatic progenitor organoids

Product Features

Overview This product is a serum-free, defined cell culture medium for establishment and maintenance of mouse hepatic progenitor organoids. These organoids, or "mini-livers", provide an in vitro organotypic culture system for studying hepatic stem and progenitor cells. Organoids grown in feature an epithelium expressing genes marking hepatic stem and progenitor cells (PROM1, AXIN2, SOX9 and CD44), ducts (KRT19 and HNF1b) and hepatocytes (HNF4a, AFP). Hepatic organoids can be passaged every 4 - 7 days, can be cryopreserved, and are primed for downstream differentiation. supports mouse hepatic organoid culture either embedded in domes or in a dilute suspension. Organoid culture enables convenient in vitro characterization of the hepatic epithelium in a physiologically relevant system and reduces the need for animal use.
Species Mouse
Cell Type Hepatic Cells
Applications Cell Culture, Expansion, Maintenance, Organoid Culture
Formulation Serum-Free

Storage & Shipping

Storage -20°C or colder
Shipping Shipped on gel packs.

For research use only. Not for clinical use.