PD 174265, EGFR tyrosine kinase inhibitor (RMML-00120835)
Cat. No.: RMML-00120835
Category: Inhibitors & Activators
INQUIRY
1 mg
Potent, selective, reversible EGFR tyrosine kinase inhibitor
Product Features
| Source | Synthetic |
|---|---|
| Purity | > 98% |
| Key Features | Potent, selective, reversible EGFR tyrosine kinase inhibitor; CAS Number: 216163-53-0; Purity: > 98%; Soluble in DMSO to 100 mM; Form / State: Solid; Source: Synthetic |
Compound Information
| Target Pathways | EGFR tyrosine kinase |
|---|---|
| Biological Description | Potent, selective, reversible EGFR tyrosine kinase inhibitor (IC50 = 0.45 nM). Antitumor agent. Cell permeable. Active in vivo and in vitro.See similar compounds |
| CAS Number | 216163-53-0 |
| Chemical Name | N-[4-[(3-Bromophenyl)amino]-6-quinazolinyl]propanamide |
| SMILES | CCC(=O)Nc1ccc2c(c1)c(ncn2)Nc1cccc(c1)Br |
| Molecular Formula | C17H15BrN4O |
| Molecular Weight | 371.24 Da |
Storage & Shipping
| Handling | Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. |
|---|---|
| Solubility | Soluble in DMSO to 100 mM |
| Storage & Shipping | Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. |
For research use only. Not for clinical use.
