Recombinant Human CXCL2 Protein (RMPP-00231014)
Cat. No.: RMPP-00231014
Category: Recombinant Protein
Research Area: Signal Transduction
INQUIRY
10 μg
2 μg
Product Features
| Source | E.coli |
|---|---|
| Purity | > 85% Densitometry. |
| Nature | Recombinant |
| Animal Free | No |
| Form | Liquid |
| Applications | WB; SDS-PAGE |
| Key Features | Expression system: E.coli; Purity: > 85% Densitometry; Suitable for: WB, SDS-PAGE |
Protein Information
| UniProt ID | Q15797 |
|---|---|
| Sequence Similarities | Belongs to the dwarfin/SMAD family. Contains 1 MH1 (MAD homology 1) domain. Contains 1 MH2 (MAD homology 2) domain. |
| Protein Length | Full length protein |
| Cellular Localization | Cytoplasm. Nucleus. Cytoplasmic in the absence of ligand. Migrates to the nucleus when complexed with SMAD4. Co-localizes with LEMD3 at the nucleus inner membrane. |
| Tissue Specificity | Ubiquitous. Highest expression seen in the heart and skeletal muscle. |
| Function | Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD1 is a receptor-regulated SMAD (R-SMAD). SMAD1/OAZ1/PSMB4 complex mediates the degradation of the CREBBP/EP300 repressor SNIP1. |
| Post-translational Modifications | Phosphorylated on serine by BMP type 1 receptor kinase.Ubiquitin-mediated proteolysis by SMAD-specific E3 ubiquitin ligase SMURF1. |
Storage & Shipping
| Shipping and Storage | Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles. pH: 7.50Constituents: 0.00174% PMSF, 0.00385% DTT, 0.79% Tris HCl, 25% Glycerol (glycerin, glycerine), 0.87% Sodium chloride |
|---|
For research use only. Not for clinical use.
