Recombinant Human FGF2 Protein (Animal Free) (RMPP-00230744)
Cat. No.: RMPP-00230744
Category: Recombinant Protein
Research Area: Immunology
INQUIRY
50 μg
1 mg
Product Features
| Source | CHO cells |
|---|---|
| Purity | > 95% SDS-PAGE. Purity is greater than 98% by SDS-PAGE gel and HPLC analyses. Endotoxin level is less than 0. 1 ng per µg (1EU/µg). |
| Nature | Recombinant |
| Animal Free | No |
| Form | Lyophilized |
| Applications | SDS-PAGE; Functional Studies |
| Key Features | Expression system: CHO cells; Purity: > 95% SDS-PAGE; Active: Yes; Suitable for: SDS-PAGE, Functional Studies |
Protein Information
| UniProt ID | P05362 |
|---|---|
| Sequence | QTSVSPSKV ILPRGGSVLV TCSTSCDQPK LLGIETPLPK KELLLPGNNR KVYELSNVQE DSQPMCYSNC PDGQSTAKTF LTVYWTPERV ELAPLPSWQP VGKNLTLRCQ VEGGAPRANL TVVLLRGEKE LKREPAVGEP AEVTTTVLVR RDHHGANFSC RTELDLRPQG LELFENTSAP YQLQTFVLPA TPPQLVSPRV LEVDTQGTVV CSLDGLFPVS EAQVHLALGD QRLNPTVTYG NDSFSAKASV SVTAEDEGTQ RLTCAVILGN QSQETLQTVT IYSFPAPNVI LTKPEVSEGT EVTVKCEAHP RAKVTLNGVP AQPLGPRAQL LLKATPEDNG RSFSCSATLE VAGQLIHKNQ TRELRVLYGP RLDERDCPGN WTWPENSQQT PMCQAWGNPL PELKCLKDGT FPLPIGESVT VTRDLEGTYL CRARSTQGEV TRKVTVNVLS PRYE |
| Sequence Similarities | Belongs to the immunoglobulin superfamily. ICAM family. Contains 5 Ig-like C2-type (immunoglobulin-like) domains. |
| Protein Length | Protein fragment |
| Cellular Localization | Membrane. |
| Function | ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation. In case of rhinovirus infection acts as a cellular receptor for the virus. |
| Post-translational Modifications | Monoubiquitinated, which is promoted by MARCH9 and leads to endocytosis. |
Storage & Shipping
| Shipping and Storage | Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C. This product is an active protein and may elicit a biological response in vivo, handle with caution. |
|---|
For research use only. Not for clinical use.
