Recombinant Human FZD3 Protein (RMPP-00230335)
Cat. No.: RMPP-00230335
Category: Growth Factors & Cytokines
Research Area: Signal Transduction
INQUIRY
10 μg
Customer Size
Product Features
| Source | E.coli |
|---|---|
| Purity | > 95% SDS-PAGE. Purity (typically >/= 98%) determined by Reducing and Non-reducing SDS-PAGE. ab179495 is sterile filtered. |
| Nature | Recombinant |
| Endotoxin Level | ≤ 1.000 Eu/µg |
| Animal Free | Yes |
| Form | Liquid |
| Applications | Functional Studies; SDS-PAGE |
| Key Features | Expression system: E.coli; Purity: > 95% SDS-PAGE; Endotoxin level: ≤ 1.000 Eu/µg; Active: Yes; Suitable for: Functional Studies, SDS-PAGE |
Protein Information
| UniProt ID | P10600 |
|---|---|
| Molecular Weight | 26 kDa |
| Sequence | ALDTNYCFRN LEENCCVRPL YIDFRQDLGW KWVHEPKGYY ANFCSGPCPY LRSADTTHST VLGLYNTLNP EASASPCCVP QDLEPLTILY YVGRTPKVEQ LSNMVVKSCK CS |
| Sequence Similarities | Belongs to the TGF-beta family. |
| Protein Length | Full length protein |
| Cellular Localization | Secreted. |
| Function | Involved in embryogenesis and cell differentiation. |
| Involvement in Disease | Defects in TGFB3 are a cause of familial arrhythmogenic right ventricular dysplasia type 1 (ARVD1); also known as arrhythmogenic right ventricular cardiomyopathy 1 (ARVC1). ARVD is an autosomal dominant disease characterized by partial degeneration of the myocardium of the right ventricle, electrical instability, and sudden death. It is clinically defined by electrocardiographic and angiographic criteria; pathologic findings, replacement of ventricular myocardium with fatty and fibrous elements, preferentially involve the right ventricular free wall. |
Storage & Shipping
| Shipping and Storage | Shipped at 4°C. Store at +4°C. Constituents: 20% Ethanol, 0.06% Acetic acid This product is an active protein and may elicit a biological response in vivo, handle with caution. |
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For research use only. Not for clinical use.
