Recombinant Human IEX1/IER3 Protein (RMPP-00230883)
Cat. No.: RMPP-00230883
Category: Recombinant Protein
Research Area: Cardiovascular
INQUIRY
20 μg
Customer Size
Product Features
| Source | HEK 293 cells |
|---|---|
| Purity | ≥ 95% SDS-PAGE. Equal or greater than 95% by HPLC |
| Nature | Recombinant |
| Endotoxin Level | ≤ 0.005 Eu/µg |
| Carrier Free | Yes |
| Animal Free | Yes |
| Form | Lyophilized |
| Applications | SDS-PAGE; HPLC; Functional Studies; Cell Culture |
| Key Features | Expression system: HEK 293 cells; Purity: ≥ 95% SDS-PAGE; Endotoxin level: ≤ 0.005 Eu/µg; Active: Yes; Suitable for: SDS-PAGE, MS, HPLC, Functional Studies, Cell Culture |
Protein Information
| UniProt ID | P10451 |
|---|---|
| Molecular Weight | 34 kDa |
| Molecular Weight Information | Mass determination by ESI-TOF. Predicted MW is 33770.58 Da. (+/- 10 Da by ESI-TOF). Observed MW is 33772.69 Da. Additional masses at 33975.94, 34179.02, 34382.33, 34584.90 and 34788.41 are due to residual O-glycans. |
| Sequence | IPVKQADSGS SEEKQLYNKY PDAVATWLNP DPSQKQNLLA PQNAVSSEET NDFKQETLPS KSNESHDHMD DMDDEDDDDH VDSQDSIDSN DSDDVDDTDD SHQSDESHHS DESDELVTDF PTDLPATEVF TPVVPTVDTY DGRGDSVVYG LRSKSKKFRR PDIQYPDATD EDITSHMESE ELNGAYKAIP VAQDLNAPSD WDSRGKDSYE TSQLDDQSAE THSHKQSRLY KRKANDESNE HSDVIDSQEL SKVSREFHSH EFHSHEDMLV VDPKSKEEDK HLKFRISHEL DSASSEVN |
| Sequence Similarities | Belongs to the osteopontin family. |
| Protein Length | Full length protein |
| Cellular Localization | Secreted. |
| Tissue Specificity | Bone. Found in plasma. |
| Function | Binds tightly to hydroxyapatite. Appears to form an integral part of the mineralized matrix. Probably important to cell-matrix interaction.Acts as a cytokine involved in enhancing production of interferon-gamma and interleukin-12 and reducing production of interleukin-10 and is essential in the pathway that leads to type I immunity. |
| Post-translational Modifications | Extensively phosphorylated on clustered serine residues.N- and O-glycosylated.Phosphorylation sites are present in the extracelllular medium. |
Storage & Shipping
| Shipping and Storage | Shipped at Room Temperature. Store at Room Temperature. pH: 7.40Constituents: 0.727% Dibasic monohydrogen potassium phosphate, 0.248% Monobasic dihydrogen potassium phosphate, 10.26% Trehalose This product is an active protein and may elicit a biological response in vivo, handle with caution. |
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For research use only. Not for clinical use.
