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Recombinant Human TIMP-2 (RMPP-00231584)

Cat. No.: RMPP-00231584

Category: Recombinant Protein

INQUIRY 2 μg 10 μg
TIMP-2 is an extracellular inhibitor of MMPs, including MMP-1, -2, -3, -7, -8, -9, -10, -12, -13, -14, -15, -16 and -19. It belongs to the I35 (TIMP) family of irreversible protease inhibitors that function as key modulators of extracellular matrix degradation during tissue development and remodeling. TIMP-2 can also act thro μgh an MMP-independent mechanism inhibiting endothelial cell proliferation in vitro and demonstrates anti-angiogenic activities in vivo. Recombinant Human TIMP-2 is a 21.8 kDa protein containing 194 amino acid residues.

Product Features

Source E.coli
Purity ≥ 95% by SDS-PAGE gel and HPLC analyses.
Nature Recombinant
Endotoxin Level < 1 Eu/μg

Protein Information

UniProt ID P16035
Molecular Weight 21.8 kDa

Storage & Shipping

Shipping and Storage Shipped on Dry Ice.

For research use only. Not for clinical use.