Recombinant Human Smad2 Protein (RMPP-00230437)
Cat. No.: RMPP-00230437
Category: Growth Factors & Cytokines
Research Area: Signal Transduction
INQUIRY
50 μg
20 μg
Product Features
| Source | HEK 293 cells |
|---|---|
| Purity | ≥ 95% SDS-PAGE. =95% by HPLC |
| Nature | Recombinant |
| Endotoxin Level | ≤ 0.005 Eu/µg |
| Carrier Free | Yes |
| Animal Free | Yes |
| Form | Lyophilized |
| Applications | Functional Studies; MS |
| Key Features | Expression system: HEK 293 cells; Purity: ≥ 95% SDS-PAGE; Endotoxin level: ≤ 0.005 Eu/µg; Active: Yes; Suitable for: Functional Studies, SDS-PAGE, HPLC, MS |
Protein Information
| UniProt ID | P41159 |
|---|---|
| Molecular Weight | 16 kDa |
| Molecular Weight Information | Predicted mass is 16061.41 Da (+/- 10Da by ESI TOF). Observed mass is 16062.15 Da |
| Sequence | VPIQKVQDDT KTLIKTIVTR INDISHTQSV SAKQRVTGLD FIPGLHPILS LSKMDQTLAV YQQVLTSLPS QNVLQIANDL ENLRDLLHLL AFSKSCSLPQ TSGLQKPESL DGVLEASLYS TEVVALSRLQ GSLQDILQQL DVSPEC |
| Sequence Similarities | Belongs to the leptin family. |
| Protein Length | Full length protein |
| Cellular Localization | Secreted. |
| Function | May function as part of a signaling pathway that acts to regulate the size of the body fat depot. An increase in the level of LEP may act directly or indirectly on the CNS to inhibit food intake and/or regulate energy expenditure as part of a homeostatic mechanism to maintain constancy of the adipose mass. |
| Involvement in Disease | Defects in LEP may be a cause of obesity (OBESITY). It is a condition characterized by an increase of body weight beyond the limitation of skeletal and physical requirements, as the result of excessive accumulation of body fat. |
Storage & Shipping
| Shipping and Storage | Shipped at Room Temperature. Store at Room Temperature. Constituents: 0.727% Dibasic monohydrogen potassium phosphate, 0.248% Monobasic dihydrogen potassium phosphate, 10.26% Trehalose This product is an active protein and may elicit a biological response in vivo, handle with caution. |
|---|
For research use only. Not for clinical use.
