Recombinant Mouse Adiponectin Protein (RMPP-00230907)
Cat. No.: RMPP-00230907
Category: Recombinant Protein
Research Area: Signal Transduction
INQUIRY
5 μg
25 μg
Product Features
| Source | E.coli |
|---|---|
| Purity | > 70% Densitometry. |
| Nature | Recombinant |
| Animal Free | No |
| Form | Liquid |
| Applications | SDS-PAGE; WB |
| Key Features | Expression system: E.coli; Purity: > 70% Densitometry; Suitable for: SDS-PAGE, WB |
Protein Information
| UniProt ID | O15198 |
|---|---|
| Molecular Weight | 86 kDa including tags |
| Sequence | MHSTTPISSLFSFTSPAVKRLLGWKQGDEEEKWAEKAVDSLVKKLKKKKG AMDELERALSCPGQPSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPD LQSHHELKPLECCEFPFGSKQKEVCINPYHYRRVETPVLPPVLVPRHSEY NPQLSLLAKFRSASLHSEPLMPHNATYPDSFQQPPCSALPPSPSHAFSQS PCTASYPHSPGSPSEPESPYQHSVDTPPLPYHATEASETQSGQPVDATAD RHVVLSIPNGDFRPVCYEEPQHWCSVAYYELNNRVGETFQASSRSVLIDG FTDPSNNRNRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECV SDSSIFVQSRNCNYQHGFHPATVCKIPSGCSLKVFNNQLFAQLLAQSVHH GFEVVYELTKMCTIRMSFVKGWGAEYHRQDVTSTPCWIEIHLHGPLQWLD KVLTQMGSPHNPISSVS |
| Sequence Similarities | Belongs to the dwarfin/SMAD family. Contains 1 MH1 (MAD homology 1) domain. Contains 1 MH2 (MAD homology 2) domain. |
| Protein Length | Full length protein |
| Cellular Localization | Cytoplasm. Nucleus. In the cytoplasm in the absence of ligand. Migration to the nucleus when complexed with SMAD4. |
| Tissue Specificity | Expressed in heart, brain, placenta, lung, skeletal muscle, prostate, testis, ovary and small intestine. Also expressed in fetal brain, lung and kidney. |
| Function | Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD9 is a receptor-regulated SMAD (R-SMAD). |
| Involvement in Disease | Pulmonary hypertension, primary, 2 |
| Post-translational Modifications | Phosphorylated on serine by BMP (bone morphogenetic proteins) type 1 receptor kinase. |
Storage & Shipping
| Shipping and Storage | Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles. pH: 7.50Constituents: 0.31% Glutathione, 0.002% PMSF, 0.004% DTT, 0.79% Tris HCl, 0.003% EDTA, 0.29% Sodium chloride |
|---|
For research use only. Not for clinical use.
