Recombinant Mouse G-CSF Protein (Active) (RMPP-00230975)
Cat. No.: RMPP-00230975
Category: Recombinant Protein
Research Area: Cardiovascular
INQUIRY
100 μg
1 mg
Product Features
| Source | E.coli |
|---|---|
| Purity | > 90% SDS-PAGE. |
| Nature | Recombinant |
| Animal Free | No |
| Form | Lyophilized |
| Applications | WB; ELISA; SDS-PAGE |
| Key Features | Expression system: E.coli; Purity: > 90% SDS-PAGE; Suitable for: WB, ELISA, SDS-PAGE |
Protein Information
| UniProt ID | O00622 |
|---|---|
| Sequence Similarities | Belongs to the CCN family. Contains 1 CTCK (C-terminal cystine knot-like) domain. Contains 1 IGFBP N-terminal domain. Contains 1 TSP type-1 domain. Contains 1 VWFC domain. |
| Protein Length | Protein fragment |
| Cellular Localization | Secreted. |
| Function | Promotes cell proliferation, chemotaxis, angiogenesis and cell adhesion. Appears to play a role in wound healing by up-regulating, in skin fibroblasts, the expression of a number of genes involved in angiogenesis, inflammation and matrix remodeling including VEGA-A, VEGA-C, MMP1, MMP3, TIMP1, uPA, PAI-1 and integrins alpha-3 and alpha-5. CYR61-mediated gene regulation is dependent on heparin-binding. Down-regulates the expression of alpha-1 and alpha-2 subunits of collagen type-1. Promotes cell adhesion and adhesive signaling through integrin alpha-6/beta-1, cell migration through integrin alpha-v/beta-5 and cell proliferation through integrin alpha-v/beta-3. |
Storage & Shipping
| Shipping and Storage | Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. Constituent: 2.68% PBS |
|---|
For research use only. Not for clinical use.
