Recombinant rat Thrombopoietin Protein (RMPP-00230992)
Cat. No.: RMPP-00230992
Category: Kinases
Research Area: Signal Transduction
INQUIRY
10 μg
Customer Size
Product Features
| Source | Baculovirus infected Sf9 cells |
|---|---|
| Purity | > 80% Densitometry. The purity of Casein Kinase 1 alpha protein (Active) was >80% as assessed by densitometry. Affinity purified. |
| Nature | Recombinant |
| Animal Free | No |
| Tags | GST tag N-Terminus |
| Form | Liquid |
| Applications | WB; Functional Studies |
| Key Features | Expression system: Baculovirus infected Sf9 cells; Purity: > 80% Densitometry; Active: Yes; Tags: GST tag N-Terminus; Suitable for: WB, Functional Studies |
Protein Information
| UniProt ID | P48729 |
|---|---|
| Molecular Weight | 62 kDa including tags |
| Sequence Similarities | Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily. Contains 1 protein kinase domain. |
| Protein Length | Full length protein |
| Cellular Localization | Cytoplasm. Cytoplasm > cytoskeleton > centrosome. Chromosome > centromere > kinetochore. Nucleus speckle. Localizes to the centrosome in interphase cells, and to kinetochore fibers during mitosis. |
| Function | Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates CTNNB1 at 'Ser-45'. May play a role in segregating chromosomes during mitosis. |
Storage & Shipping
| Shipping and Storage | Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles. pH: 7.50Constituents: 0.307% Glutathione, 0.00174% PMSF, 0.00385% DTT, 0.79% Tris HCl, 0.00292% EDTA, 25% Glycerol (glycerin, glycerine), 0.87% Sodium chloride This product is an active protein and may elicit a biological response in vivo, handle with caution. |
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For research use only. Not for clinical use.
