Recombinant rhesus Monkey CD4 Protein (Fc Chimera Active) (RMPP-00230279)
Cat. No.: RMPP-00230279
Category: Recombinant Protein
Research Area: Epigenetics and Nuclear Signaling
INQUIRY
100 μg
Customer Size
Product Features
| Source | Baculovirus infected insect cells |
|---|---|
| Purity | ≥ 79 % SDS-PAGE. Protein was purified by affinity chromatography and gel filtration. |
| Nature | Recombinant |
| Animal Free | No |
| Tags | GST tag N-Terminus |
| Modifications | mutated H611A |
| Form | Liquid |
| Applications | Functional Studies; SDS-PAGE |
| Key Features | Expression system: Baculovirus infected insect cells; Purity: ≥ 79% SDS-PAGE; Active: Yes; Tags: GST tag N-Terminus; Suitable for: Functional Studies, SDS-PAGE |
Protein Information
| UniProt ID | Q9UBN7 |
|---|---|
| Molecular Weight | 161 kDa including tags |
| Sequence | MSPILGYWKIKGLVQPTRLLLEYLEEKYEEHLYERDEGDKWRNKKFELGL EFPNLPYYIDGDVKLTQSMAIIRYIADKHNMLGGCPKERAEISMLEGAVL DIRYGVSRIAYSKDFETLKVDFLSKLPEMLKMFEDRLCHKTYLNGDHVTH PDFMLYDALDVVLYMDPMCLDAFPKLVCFKKRIEAIPQIDKYLKSSKYIA WPLQGWQATFGGGDHPPKSDPMGHHHHHHGRRRASVAAGILVPRGSPGLD GIYARGIQMTSTGQDSTTTRQRRSRQNPQSPPQDSSVTSKRNIKKGAVPR SIPNLAEVKKKGKMKKLGQAMEEDLIVGLQGMDLNLEAEALAGTGLVLDE QLNEFHCLWDDSFPEGPERLHAIKEQLIQEGLLDRCVSFQARFAEKEELM LVHSLEYIDLMETTQYMNEGELRVLADTYDSVYLHPNSYSCACLASGSVL RLVDAVLGAEIRNGMAIIRPPGHHAQHSLMDGYCMFNHVAVAARYAQQKH RIRRVLIVDWDVHHGQGTQFTFDQDPSVLYFSIHRYEQGRFWPHLKASNW STTGFGQGQGYTINVPWNQVGMRDADYIAAFLHVLLPVALEFQPQLVLVA AGFDALQGDPKGEMAATPAGFAQLTHLLMGLAGGKLILSLEGGYNLRALA EGVSASLHTLLGDPCPMLESPGAPCRSAQASVSCALEALEPFWEVLVRST ETVERDNMEEDNVEESEEEGPWEPPVLPILTWPVLQSRTGLVYDQNMMNH CNLWDSHHPEVPQRILRIMCRLEELGLAGRCLTLTPRPATEAELLTCHSA EYVGHLRATEKMKTRELHRESSNFDSIYICPSTFACAQLATGAACRLVEA VLSGEVLNGAAVVRPPGHAAEQDAACGFCFFNSVAVAARHAQTISGHALR ILIVDWDVHHGNGTQHMFEDDPSVLYVSLHRYDHGTFFPMGDEGASSQIG RAAGTGFTVNVAWNGPRMGDADYLAAWHRLVLPIAYEFNPELVLVSAGFD AARGDPLGGCQVSPEGYAHLTHLLMGLASGRIILILEGGYNLTSISESMA ACTRSLLGDPPPLLTLPRPPLSGALASITETIQVHRRYWRSLRVMKVEDR EGPSSSKLVTKKAPQPAKPRLAERMTTREKKVLEAGMGKVTSASFGEEST PGQTNSETAVVALTQDQPSEAATGGATLAQTISEAAIGGAMLGQTTSEEA VGGATPDQTTSEETVGGAILDQTTSEDAVGGATLGQTTSEEAVGGATLAQ TTSEAAMEGATLDQTTSEEAPGGTELIQTPLASSTDHQTPPTSPVQGTTP QISPSTLIGSLRTLELGSESQGASESQAPGEENLLGEAAGGQDMADSMLM QGSRGLTDQAIFYAVTPLPWCPHLVAVCPIPAAGLDVTQPCGDCGTIQEN WVCLSCYQVYCGRYINGHMLQHHGNSGHPLVLSYIDLSAWCYYCQAYVHH QALLDVKNIAHQNKFGEDMPHPH |
| Sequence Similarities | Belongs to the histone deacetylase family. HD type 2 subfamily. Contains 1 UBP-type zinc finger. |
| Protein Length | Full length protein |
| Cellular Localization | Nucleus. Cytoplasm. It is mainly cytoplasmic, where it is associated with microtubules. |
| Function | Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes (By similarity). Plays a central role in microtubule-dependent cell motility via deacetylation of tubulin. |
| Post-translational Modifications | Ubiquitinated. Its polyubiquitination however does not lead to its degradation.Sumoylated in vitro. |
Storage & Shipping
| Shipping and Storage | Shipped on Dry Ice. Store at -80°C. Avoid freeze / thaw cycle. pH: 7.5Constituents: 0.79% Tris HCl, 0.03% (R*,R*)-1,4-Dimercaptobutan-2,3-diol, 0.38% Potassium chloride, 0.79% Sodium chloride, 0.06% EDTA, 10% Glycerol (glycerin, glycerine) This product is an active protein and may elicit a biological response in vivo, handle with caution. |
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For research use only. Not for clinical use.
