Recombinant Woodchuck Interferon gamma Protein (His tag)

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Recombinant Woodchuck Interferon gamma Protein (His tag) (RMPP-00230406)

Cat. No.: RMPP-00230406

Category: Recombinant Protein

Research Area: Immunology

INQUIRY 100 μg Customer Size

Product Features

Source	HEK 293 cells
Purity	> 95% SDS-PAGE.
Nature	Recombinant
Endotoxin Level	< 1.000 Eu/µg
Animal Free	No
Tags	Fc tag C-Terminus
Form	Lyophilized
Applications	Functional Studies; SDS-PAGE; ELISA
Key Features	Expression system: HEK 293 cells; Purity: > 95% SDS-PAGE; Endotoxin level: < 1.000 Eu/µg; Active: Yes; Tags: Fc tag C-Terminus; Suitable for: Functional Studies, SDS-PAGE, ELISA

Protein Information

UniProt ID	P42081
Molecular Weight	52 kDa
Sequence Similarities	Contains 1 Ig-like C2-type (immunoglobulin-like) domain. Contains 1 Ig-like V-type (immunoglobulin-like) domain.
Protein Length	Protein fragment
Cellular Localization	Membrane.
Tissue Specificity	Expressed by activated B-lymphocytes and monocytes.
Function	Receptor involved in the costimulatory signal essential for T-lymphocyte proliferation and interleukin-2 production, by binding CD28 or CTLA-4. May play a critical role in the early events of T-cell activation and costimulation of naive T-cells, such as deciding between immunity and anergy that is made by T-cells within 24 hours after activation. Isoform 2 interferes with the formation of CD86 clusters, and thus acts as a negative regulator of T-cell activation.
Post-translational Modifications	Polyubiquitinated; which is promoted by MARCH8 and results in endocytosis and lysosomal degradation.

Storage & Shipping

Shipping and Storage	Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. pH: 7.4Constituents: 0.75% Glycine, 0.48% Tris, L-Arginine, Sodium chlorideLyophilized from 0.22 µm filtered solution. 5-10% trehalose is commonly used for freeze drying, and after reconstitution, the trehalose is mostly about 3-5% This product is an active protein and may elicit a biological response in vivo, handle with caution.

Shipping and Storage

Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
pH: 7.4Constituents: 0.75% Glycine, 0.48% Tris, L-Arginine, Sodium chlorideLyophilized from 0.22 µm filtered solution.
5-10% trehalose is commonly used for freeze drying, and after reconstitution, the trehalose is mostly about 3-5%
This product is an active protein and may elicit a biological response in vivo, handle with caution.

For research use only. Not for clinical use.