Rottlerin, Kinase inhibitor (RMML-00120584)
Cat. No.: RMML-00120584
Category: Inhibitors & Activators
INQUIRY
50 mg
10 mg
Kinase inhibitor
Product Features
| Source | Synthetic |
|---|---|
| Key Features | Kinase inhibitor; CAS Number: 82-08-6; Soluble in DMSO to 100 mM; Form / State: Solid; Source: Synthetic |
Compound Information
| Target Pathways | Kinase |
|---|---|
| Biological Description | Originally reported to inhibit PKC isoforms, especially PKCδ and CAM-KIII. Also inhibits MAPKAP-K2 and PRAK (IC50 values are 5.4 and 1.9 μM, respectively), CHK2, PLK1, PIM3 and SRPK1. |
| CAS Number | 82-08-6 |
| Chemical Name | 3'-[(8-Cinnamoyl-5,7-dihydroxy-2,2-dimethyl-2H-1-benzopyran-6-yl)methyl]-2',4',6'-trihydroxy-5'-methylacetophenone |
| SMILES | CC(=O)c4c(O)c(Cc2c(O)c(c1OC(C)(C)C=Cc1c2O)C(=O)/C=C/c3ccccc3)c(O)c(C)c4O |
| Molecular Formula | C30H28O8 |
| Molecular Weight | 516.55 Da |
| PubChem Identifier | 5281847 |
Storage & Shipping
| Handling | Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. |
|---|---|
| Solubility | Soluble in DMSO to 100 mM |
| Storage & Shipping | Shipped at room temperature. Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. |
For research use only. Not for clinical use.
