SAHA (Vorinostat), HDAC inhibitor (RMML-00120767)
Cat. No.: RMML-00120767
Category: Inhibitors & Activators
INQUIRY
50 mg
10 mg
Potent non-selective HDAC inhibitor
Product Features
| Source | Synthetic |
|---|---|
| Purity | > 98% |
| Key Features | Potent non-selective HDAC inhibitor; CAS Number: 149647-78-9; Purity: > 98%; Soluble in ethanol to 50 mM (with warming) and in DMSO to 100mM; Form / State: Solid; Source: Synthetic |
Compound Information
| Target Pathways | HDAC |
|---|---|
| Biological Description | Potent non-selective HDAC inhibitor (IC50 values are 10 and 20 nM for HDAC1 and HDAC3, respectively). Induces apoptosis and shows antiproliferative effects against cancer cell lines (IC50 = 3 - 8 μM). Antitumor effects in vivo. No effect on class III HDACs. Orally active. |
| Alternative Names | Vorinostat |
| CAS Number | 149647-78-9 |
| Chemical Name | N1-Hydroxy-N8-phenyloctanediamide |
| SMILES | C1=CC=C(C=C1)NC(=O)CCCCCCC(=O)NO |
| Molecular Formula | C14H20N2O3 |
| Molecular Weight | 264.32 Da |
| PubChem Identifier | 5311 |
Storage & Shipping
| Handling | Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Toxic, refer to SDS for further information |
|---|---|
| Solubility | Soluble in ethanol to 50 mM (with warming) and in DMSO to 100mM |
| Storage & Shipping | Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. |
For research use only. Not for clinical use.
