AMD 3465 hexahydrobromide, CXCR4 antagonist (RMML-00120738)
Cat. No.: RMML-00120738
Category: Inhibitors & Activators
INQUIRY
50 mg
10 mg
Potent and selective CXCR4 antagonist
Product Features
| Source | Synthetic |
|---|---|
| Purity | > 97% |
| Key Features | Potent and selective CXCR4 antagonist; CAS Number: 185991-07-5; Purity: > 97%; Soluble in water to 50 mM and in DMSO to 25 mM; Form / State: Solid; Source: Synthetic |
Compound Information
| Target Pathways | CXCR4 |
|---|---|
| Biological Description | Potent and selective CXCR4 antagonist. Shows 8-fold greater affinity than AMD 3100 (ab120718). Potent HIV entry inhibitor (IC50 = ~10 nM). Additionally mobilizes stem cells in vivo. |
| CAS Number | 185991-07-5 |
| Chemical Name | N-[[4-(1,4,8,11-Tetraazacyclotetradec-1-ylmethyl)phenyl]methyl]-2-pyridinemethanamine hexahydrobromide |
| SMILES | Br.Br.Br.Br.Br.Br.C3NCCCNCCN(Cc2ccc(CNCc1ccccn1)cc2)CCCNC3 |
| Molecular Formula | C24H38N6.6HBr |
| Molecular Weight | 896.08 Da |
| PubChem Identifier | 483559 |
Storage & Shipping
| Handling | Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. |
|---|---|
| Solubility | Soluble in water to 50 mM and in DMSO to 25 mM |
| Storage & Shipping | Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. |
For research use only. Not for clinical use.
