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SB 203580 hydrochloride, p38 MAPK inhibitor

SB 203580 hydrochloride, p38 MAPK inhibitor (RMML-00120694)

Cat. No.: RMML-00120694

Category: Inhibitors & Activators

INQUIRY 10 mg
p38 MAPK inhibitor; water soluble

Product Features

Source Synthetic
Key Features p38 MAPK inhibitor; water soluble; CAS Number: 869185-85-3; Soluble in water to 25 mM; Form / State: Solid; Source: Synthetic

Compound Information

Target Pathways p38 MAPK
Biological Description Water soluble, cell-permeable p38 MAPK inhibitor. Shows selectivity over many other kinases but also shown to have some inhibitory activity against GAK, CK1, RIP2 c-Raf and GSK3.
CAS Number 869185-85-3
Chemical Name 4-[4-(4-Fluorophenyl)-2-[4-(methylsulfinyl)phenyl]-1H-imidazol-5-yl]pyridine hydrochloride
SMILES Cl.CS(=O)c1ccc(cc1)c2nc(c(n2)c3ccncc3)c4ccc(F)cc4
Molecular Formula C21H16FN3OS.HCl
Molecular Weight 413.90 Da
PubChem Identifier 16760644

Storage & Shipping

Handling Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Refer to SDS for further information.
Solubility Soluble in water to 25 mM
Storage & Shipping Store at 4°C. Store under desiccating conditions. The product can be stored for up to 12 months.

For research use only. Not for clinical use.