SU-5402, VEGFR and FGFR inhibitor (RMML-00120827)
Cat. No.: RMML-00120827
Category: Inhibitors & Activators
INQUIRY
5 mg
1 mg
Potent, selective VEGFR and FGFR inhibitor
Product Features
| Source | Synthetic |
|---|---|
| Purity | > 97% |
| Key Features | Potent, selective VEGFR and FGFR inhibitor; CAS Number: 215543-92-3; Purity: > 97%; Soluble in DMSO to 100 mM; Form / State: Solid; Source: Synthetic |
Compound Information
| Target Pathways | VEGFR, FGFR |
|---|---|
| Biological Description | Potent, selective VEGFR and FGFR inhibitor (IC50 values are 0.02 (VEGFR2), 0.03 (FGFR1), 0.51 (PDGFRβ) and >100 μM (EGFR)). Attenuates integrin β4-induced differentiation of neural stem cells. Shows antitumor effects in vivo. |
| CAS Number | 215543-92-3 |
| Chemical Name | 2-[(1,2-Dihydro-2-oxo-3H-indol-3-ylidene)methyl]-4-methyl-1H-pyrrole-3-propanoic acid |
| SMILES | Cc1c[nH]c(c1CCC(=O)O)/C=C2/c3ccccc3NC2=O |
| Molecular Formula | C17H16N2O3 |
| Molecular Weight | 296.33 Da |
| PubChem Identifier | 5289418 |
Storage & Shipping
| Handling | Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. |
|---|---|
| Solubility | Soluble in DMSO to 100 mM |
| Storage & Shipping | Store at 4°C. The product can be stored for up to 12 months. |
For research use only. Not for clinical use.
