Teneligliptin, DPP-4 inhibitor (RMML-00120789)
Cat. No.: RMML-00120789
Category: Inhibitors & Activators
INQUIRY
10 mg
50 mg
Potent, long-lasting DPP-4 inhibitor
Product Features
| Source | Synthetic |
|---|---|
| Purity | > 98% |
| Key Features | Potent, long-lasting DPP-4 inhibitor; CAS Number: 760937-92-6; Purity: > 98%; Soluble in water to 159.01 mM, in DMSO to 159.01 mM and in ethanol to 27.03 mM.; Form / State: Solid; Source: Synthetic |
Compound Information
| Target Pathways | DPP-4 |
|---|---|
| Biological Description | Potent, long-lasting DPP-4 (dipeptidylpeptidase-4) inhibitor. Competitively inhibits human plasma, rat plasma, and human recombinant DPP-4 in vitro (IC50 = ~ 1 nM). Attenuates lipogenesis in the liver by activating AMPK and downregulating the expression of genes involved in lipogenesis. Improves metabolic abnormalities in a mouse model of postmenopausal obesity. |
| Alternative Names | Teneglucon, Tenelia, Tenepure, Teneria |
| CAS Number | 760937-92-6 |
| Chemical Name | ((2S,4S)-4-(4-(3-methyl-1-phenyl-1H-pyrazol-5-yl)piperazin-1-yl)pyrrolidin-2-yl)(thiazolidin-3-yl)methanone |
| SMILES | CC1=NN(C(=C1)N2CCN(CC2)C3CC(NC3)C(=O)N4CCSC4)C5=CC=CC=C5 |
| Molecular Formula | C22H30N6OS |
| Molecular Weight | 426.58 Da |
| PubChem Identifier | 11949652 |
Storage & Shipping
| Handling | Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. |
|---|---|
| Solubility | Soluble in water to 159.01 mM, in DMSO to 159.01 mM and in ethanol to 27.03 mM. |
| Storage & Shipping | Shipped at 4°C. Store at -20°C. Store in the dark. Store under desiccating conditions. |
For research use only. Not for clinical use.
