WAY 262611, Wnt pathway activator (RMML-00121097)
Cat. No.: RMML-00121097
Category: Inhibitors & Activators
INQUIRY
25 mg
5 mg
Wnt pathway activator
Product Features
Source | Synthetic |
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Purity | > 97% |
Key Features | Wnt pathway activator; Purity: > 97%; Soluble in ethanol to 75 mM and in DMSO to 75 mM; Form / State: Solid; Source: Synthetic |
Compound Information
Target Pathways | WNT |
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Biological Description | Wnt pathway activator. Selectively inhibits Dkk1 with no GSK-3β inhibition. TCF-Luciferase agonist (EC50 = 0.63 µM). Increases bone formation rate in vivo. Orally active. |
Chemical Name | [1-(4-Naphthalen-2-ylpyrimidin-2-yl)piperidin-4-yl]methanamine |
SMILES | C1CN(CCC1CN)C2=NC=CC(=N2)C3=CC4=CC=CC=C4C=C3 |
Molecular Formula | C20H22N4 |
Molecular Weight | 318.40 Da |
PubChem Identifier | 25199517 |
Storage & Shipping
Handling | Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. |
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Solubility | Soluble in ethanol to 75 mM and in DMSO to 75 mM |
Storage & Shipping | Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. |
For research use only. Not for clinical use.