WNT7A Antibody Pair - BSA and Azide free (RMAB-0252039)
Cat. No.: RMAB-0252039
Category: Antibody Pair
INQUIRY
10 x 96 tests
Human WNT7A Antibody Pair is a matched pair of unconjugated recombinant rabbit monoclonal capture and detection antibodies used to quantify WNT7A in sandwich ELISAs and many other pair-based applications._x000D_
Product Features
| Conjugate | Unconjugated capture and detector antibodies |
|---|---|
| Species Reactivity | Mouse, Rat, Human |
| Range | 15.625 pg/mL - 4000 pg/mL |
| Applications | Sandwich ELISA |
| Key Features | Unconjugated capture and detector antibodies; Adaptable to any antibody pair-based assay format; Antibody concentration ~ 1 mg/mL; BSA and azide free buffer - ready for conjugation; Reacts with: Mouse, Rat, Human |
Target Information
| Target Symbol | WNT7A |
|---|---|
| Target Name | Protein Wnt-7a |
| UniProt ID | O00755 |
| Cellular Localization | Secreted > extracellular space > extracellular matrix. |
| Function | Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. Signaling by Wnt-7a allows sexually dimorphic development of the mullerian ducts. |
| Involvement in Disease | Defects in WNT7A are the cause of limb/pelvis-hypoplasia/aplasia syndrome (LPHAS); also known asof ulna and fibula with severe limb deficiency. LPHAS is a limb-malformation disorder characterized by various degrees of limb aplasia/hypoplasia and joint dysplasia.Defects in WNT7A are a cause of Fuhrmann syndrome (FUHRS); also known as fibular aplasia or hypoplasia femoral bowing and poly- syn- and oligodactyly. Fuhrmann syndrome is a distinct limb-malformation disorder characterized also by various degrees of limb aplasia/hypoplasia and joint dysplasia. |
| Sequence Similarities | Belongs to the Wnt family. |
Storage & Shipping
| Storage & Shipping | Store at 4°C. Please refer to protocols. |
|---|
For research use only. Not for clinical use.
