YC-1, guanylyl cyclase activator (RMML-00120871)
Cat. No.: RMML-00120871
Category: Inhibitors & Activators
INQUIRY
10 mg
50 mg
Reversible soluble guanylyl cyclase activator
Product Features
| Source | Synthetic |
|---|---|
| Purity | > 99% |
| Key Features | Reversible soluble guanylyl cyclase activator; CAS Number: 170632-47-0; Purity: > 99%; Soluble in ethanol to 50 mM and in DMSO to 50 mM; Form / State: Solid; Source: Synthetic |
Compound Information
| Target Pathways | guanylyl cyclase |
|---|---|
| Biological Description | Reversible soluble guanylyl cyclase activator (EC50 = 18.6 μM). NO-independent. Induces a concentration dependent increase in cGMP in vitro. Reduces blood-brain barrier permeability throμgh HIF-1 inhibiton in vivo. |
| CAS Number | 170632-47-0 |
| Chemical Name | 5-[1-(Phenylmethyl)-1H-indazol-3-yl]-2-furanmethanol |
| SMILES | OCC1=CC=C(C2=NN(CC3=CC=CC=C3)C4=C2C=CC=C4)O1 |
| Molecular Formula | C19H16N2O2 |
| Molecular Weight | 304.35 Da |
| PubChem Identifier | 5712 |
Storage & Shipping
| Handling | Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. |
|---|---|
| Solubility | Soluble in ethanol to 50 mM and in DMSO to 50 mM |
| Storage & Shipping | Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. |
For research use only. Not for clinical use.
