ZM306416 hydrochloride, VEGFR1/2 tyrosine kinase activity inhibitor (RMML-00120742)
Cat. No.: RMML-00120742
Category: Inhibitors & Activators
INQUIRY
25 mg
5 mg
Potent and selective VEGFR1/2 tyrosine kinase activity inhibitor
Product Features
| Source | Synthetic |
|---|---|
| Purity | > 98% |
| Key Features | Potent and selective VEGFR1/2 tyrosine kinase activity inhibitor; CAS Number: 196603-47-1; Purity: > 98%; Soluble in DMSO to 10 mM; Form / State: Solid; Source: Synthetic |
Compound Information
| Target Pathways | VEGFR1/2 tyrosine kinase activity |
|---|---|
| Biological Description | Potent and selective VEGFR1/2 inhibitor (IC50 values are 100 nM and 2 μM for KDR and Flt respectively). Shows antiproliferative effects in vivo. Orally active. |
| CAS Number | 196603-47-1 |
| Chemical Name | 4-[(4'-Chloro-2'-fluoro)phenylamino]-6,7-dimethoxyquinazoline hydrochloride |
| SMILES | COC1=C(C=C2C(=C1)C(=NC=N2)NC3=C(C=C(C=C3)Cl)F)OC |
| Molecular Formula | C16H13ClFN3O2.HCl |
| Molecular Weight | 370.12 Da |
| PubChem Identifier | 5329006 |
Storage & Shipping
| Handling | Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. |
|---|---|
| Solubility | Soluble in DMSO to 10 mM |
| Storage & Shipping | Store at room temperature. The product can be stored for up to 12 months. |
For research use only. Not for clinical use.
