Anti-CD11a Antibody - Rabbit IgG (Chimeric) (RMAB-0250175)
Cat. No.: RMAB-0250175
Category: Primary Antibodies
INQUIRY
200 μg
Customer Size
Rabbit monoclonal to CD11a - Chimeric
Product Features
Isotype | IgG |
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Clonality | Monoclonal |
Host Species | Rabbit |
Clone Number | hu1124 (Efalizumab) |
Form | Liquid |
Purity | Protein A purified |
Species Reactivity | Human, Rat |
Immunogen | Recombinant fragment corresponding to Human CD11a. |
Applications | Flow Cyt, IHC-P |
Key Features | Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply; Rabbit monoclonal to CD11a - Chimeric; Suitable for: Flow Cyt, IHC-P; Reacts with: Rat, Human |
Target Information
Target Symbol | ITGAL |
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Target Name | Integrin alpha-L |
UniProt ID | P20701 |
Cellular Localization | Membrane. |
Function | Integrin alpha-L/beta-2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. It is involved in a variety of immune phenomena including leukocyte-endothelial cell interaction, cytotoxic T-cell mediated killing, and antibody dependent killing by granulocytes and monocytes. |
Domain | The integrin I-domain (insert) is a VWFA domain. Integrins with I-domains do not undergo protease cleavage. |
Sequence Similarities | Belongs to the integrin alpha chain family. Contains 7 FG-GAP repeats. Contains 1 VWFA domain. |
Storage & Shipping
Storage Buffer | Preservative: 0.02% Proclin 300; Constituent: 99.98% PBS |
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Storage & Shipping | Shipped at 4°C. Store at 4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C. Avoid freeze / thaw cycle. |
For research use only. Not for clinical use.