Anti-CD40 Antibody (RMAB-0250354)
Cat. No.: RMAB-0250354
Category: Primary Antibodies
INQUIRY
100 μL
Customer Size
Rabbit monoclonal to CD40
Product Features
| Isotype | IgG |
|---|---|
| Clonality | Monoclonal |
| Host Species | Rabbit |
| Clone Number | EPR20735 |
| Form | Liquid |
| Purity | Protein A purified |
| Species Reactivity | Human |
| Immunogen | Recombinant fragment. |
| Applications | WB, IHC-P, Flow Cyt, IP, ICC/IF |
| Key Features | Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply; Rabbit monoclonal to CD40; Suitable for: WB, IHC-P, Flow Cyt, IP, ICC/IF; Knockout validated; Reacts with: Human |
Target Information
| Target Symbol | CD40 |
|---|---|
| Target Name | Tumor necrosis factor receptor superfamily member 5 |
| UniProt ID | P25942 |
| Cellular Localization | Secreted and Cell membrane. |
| Function | Receptor for TNFSF5/CD4LG. |
| Involvement in Disease | Defects in CD4 are the cause of hyper-IgM immunodeficiency syndrome type 3 (HIGM3); also known as hyper-IgM syndrome 3. HIGM3 is an autosomal recessive disorder which includes an inability of B cells to undergo isotype switching, one of the final differentiation steps in the humoral immune system, an inability to mount an antibody-specific immune response, and a lack of germinal center formation. |
| Sequence Similarities | Contains 4 TNFR-Cys repeats. |
Storage & Shipping
| Storage Buffer | pH: 7.2; Preservative: 0.01% Sodium azide; Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA |
|---|---|
| Storage & Shipping | Shipped at 4°C. Store at 4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. |
For research use only. Not for clinical use.
