Anti-TGF beta 3 Antibody (RMAB-0251148)
Cat. No.: RMAB-0251148
Category: Primary Antibodies
INQUIRY
100 μL
10 µL
Rabbit monoclonal to TGF beta 3
Product Features
Isotype | IgG |
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Clonality | Monoclonal |
Host Species | Rabbit |
Clone Number | EPR27093-72 |
Form | Liquid |
Purity | Protein A purified |
Species Reactivity | Human, Mouse, Rat |
Immunogen | Recombinant fragment. |
Applications | WB, Dot blot, ICC/IF, Flow Cyt (Intra), IP |
Key Features | Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply; Rabbit monoclonal to TGF beta 3; Suitable for: WB, Dot blot, ICC/IF, Flow Cyt (Intra), IP; Reacts with: Mouse, Rat, Human |
Target Information
Target Symbol | TGFB3 |
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Target Name | Transforming growth factor beta-3 proprotein |
UniProt ID | P10600 |
Cellular Localization | Secreted. |
Function | Involved in embryogenesis and cell differentiation. |
Involvement in Disease | Defects in TGFB3 are a cause of familial arrhythmogenic right ventricular dysplasia type 1 (ARVD1); also known as arrhythmogenic right ventricular cardiomyopathy 1 (ARVC1). ARVD is an autosomal dominant disease characterized by partial degeneration of the myocardium of the right ventricle, electrical instability, and sudden death. It is clinically defined by electrocardiographic and angiographic criteria; pathologic findings, replacement of ventricular myocardium with fatty and fibrous elements, preferentially involve the right ventricular free wall. |
Sequence Similarities | Belongs to the TGF-beta family. |
Storage & Shipping
Storage Buffer | pH: 7.2; Preservative: 0.01% Sodium azide; Constituents: 59% PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA |
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Storage & Shipping | Shipped at 4°C. Store at 4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. |
For research use only. Not for clinical use.