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Anti-MAP2 Antibody - Neuronal Marker

Anti-MAP2 Antibody - Neuronal Marker (RMAB-0250838)

Cat. No.: RMAB-0250838

Category: Primary Antibodies

INQUIRY 100 μg Customer Size
Rabbit polyclonal to MAP2 - Neuronal Marker

Product Features

Isotype IgG
Clonality Polyclonal
Host Species Rabbit
Form Liquid
Purity Immunogen affinity purified
Species Reactivity Human, Mouse, Rat
Immunogen Synthetic peptide within Rat MAP2 aa 1-1 (N terminal) conjugated to keyhole limpet haemocyanin. The exact sequence is proprietary.
Applications IHC-P, WB, ICC/IF
Key Features Rabbit polyclonal to MAP2 - Neuronal Marker; Suitable for: IHC-P, WB, ICC/IF; Reacts with: Mouse, Rat, Human; Isotype: IgG

Target Information

Target Symbol MAP2
Target Name Microtubule-associated protein 2
UniProt ID P11137
Cellular Localization Cytoplasm, cytoskeleton.
Function The exact function of MAP2 is unknown but MAPs may stabilize the microtubules against depolymerization. They also seem to have a stiffening effect on microtubules.
Post-translational Modifications Phosphorylated at serine residues in K-X-G-S motifs by MAP/microtubule affinity-regulating kinase (MARK1 or MARK2), causing detachment from microtubules, and their disassembly (By similarity). Isoform 2 is probably phosphorylated by PKA at Ser-323, Ser-354 and Ser-386 and by FYN at Tyr-67.
Sequence Similarities Contains 3 Tau/MAP repeats.

Storage & Shipping

Storage Buffer pH: 7.40; Preservative: 0.02% Sodium azide; Constituent: PBSBatches of this product that have a concentration < 1mg/ml may have BSA added as a stabilising agent. If you would like information about the formulation of a specific lot, please contact our scientific support team who will be happy to help.
Storage & Shipping Shipped at 4°C. Store at 4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

For research use only. Not for clinical use.