Anti-MEIS1 Monoclonal Antibody (RMAB-0251390)
Cat. No.: RMAB-0251390
Category: Primary Antibodies
Research Area: Stem Cells, Epigenetics
INQUIRY
100 μL
Customer Size
Anti-MEIS1 Monoclonal Antibody. Tested in Flow Cytometry, IP, WB applications. This antibody reacts with Human, Mouse, Rat.
Product Features
| Isotype | IgG |
|---|---|
| Clonality | Monoclonal |
| Host Species | Rabbit |
| Form | Liquid |
| Species Reactivity | Human, Mouse, Rat |
| Immunogen | Recombinant fragment. |
| Applications | WB, Flow Cyt, IHC, IF, ICC, IP |
Target Information
| Target Symbol | MEIS1 |
|---|---|
| Target Name | Homeobox protein Meis1 |
| UniProt ID | O00470 |
| Function | Acts as a transcriptional regulator of PAX6. Acts as a transcriptional activator of PF4 in complex with PBX1 or PBX2. Required for hematopoiesis, megakaryocyte lineage development and vascular patterning. May function as a cofactor for HOXA7 and HOXA9 in the induction of myeloid leukemias. |
| Involvement in Disease | Defects in MEIS1 could be a cause of susceptibility to restless legs syndrome type 7 (RLS7). Restless legs syndrome (RLS) is a neurologic sleep/wake disorder characterized by uncomfortable and unpleasant sensations in the legs that appear at rest, usually at night, inducing an irresistible desire to move the legs. The disorder results in nocturnal insomnia and chronic sleep deprivation. |
| Sequence Similarities | Belongs to the TALE/MEIS homeobox family. Contains 2 homeobox DNA-binding domain. |
Storage & Shipping
| Storage Buffer | Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles. |
|---|---|
| Storage & Shipping | Dry Ice |
For research use only. Not for clinical use.
