Anti-p75 NGF Receptor Antibody (RMAB-0250947)
Cat. No.: RMAB-0250947
Category: Primary Antibodies
INQUIRY
10 μL
100 μL
Rabbit monoclonal to p75 NGF Receptor
Product Features
| Isotype | IgG |
|---|---|
| Clonality | Monoclonal |
| Host Species | Rabbit |
| Clone Number | EP1039Y |
| Form | Liquid |
| Purity | Protein A purified |
| Species Reactivity | Human, Mouse, Rat |
| Immunogen | Synthetic peptide within Human p75 NGF Receptor aa 35-45. The exact sequence is proprietary. |
| Applications | WB, IP, IHC-P, ICC/IF, Flow Cyt (Intra) |
| Key Features | Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply; Rabbit monoclonal to p75 NGF Receptor; Suitable for: WB, IP, IHC-P, ICC/IF, Flow Cyt (Intra); Reacts with: Mouse, Rat, Human |
Target Information
| Target Symbol | NGFR |
|---|---|
| Target Name | Tumor necrosis factor receptor superfamily member 16 |
| UniProt ID | P08138 |
| Cellular Localization | Membrane. |
| Function | Low affinity receptor which can bind to NGF, BDNF, NT-3, and NT-4. Can mediate cell survival as well as cell death of neural cells. |
| Post-translational Modifications | N- and O-glycosylated. O-linked glycans consist of Gal(1-3)GalNAc core elongated by 1 or 2 NeuNAc. Phosphorylated on serine residues. |
| Domain | Death domain is responsible for interaction with RANBP9.The extracellular domain is responsible for interaction with NTRK1. |
| Sequence Similarities | Contains 1 death domain. Contains 4 TNFR-Cys repeats. |
Storage & Shipping
| Storage Buffer | pH: 7.20; Preservative: 0.01% Sodium azide; Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.5% BSA |
|---|---|
| Storage & Shipping | Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. |
For research use only. Not for clinical use.
