Bleomycin (RMML-00120132)
Cat. No.: RMML-00120132
Category: Inhibitors & Activators
INQUIRY
1 mg
5 mg
Bleomycin is a glycopeptide-derived antibiotic, isolated from the bacterium Streptomyces verticillus, that creates DNA strand scission and exhibits antitumor activity against squamous cell carcinomas and malignant lymphomas. Bleomycin induces lung injury leading to acute inflammatory response and pulmonary fibrosis. This product is supplied as the sulfate salt of the molecule. Induces single- and double-strand DNA breaks in tumor cells.
Product Features
| Purity | ≥ 95% (mixture of A2 and B2) |
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Compound Information
| Alternative Names | Blenoxane |
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| CAS Number | 9041-93-4 (for A2), 9060-10-0 (for B2) |
| Molecular Formula | 3-[[2-[2-[2-[[(2S,3R)-2-[[(2S,3S,4R)-4-[[(2S,3R)-2-[[6-amino-2-[(1S)-3-amino-1-[[(2S)-2,3-diamino-3-oxopropyl]amino]-3-oxopropyl]-5-methylpyrimidine-4-carbonyl]amino]-3-[(2R,3S,4S,5S,6S)-3-[(2R,3S,4S,5R,6R)-4-carbamoyloxy-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3-(1H-imidazol-5-yl)propanoyl]amino]-3-hydroxy-2-methylpentanoyl]amino]-3-hydroxybutanoyl]amino]ethyl]-1,3-thiazol-4-yl]-1,3-thiazole-4-carbonyl]amino]propyl-dimethylsulfanium, sulfate |
| Molecular Weight | 1415.6 Da (for A2), 1425.5 Da (for B2) |
Storage & Shipping
| Handling | Refer to SDS for further information. |
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For research use only. Not for clinical use.
