Ruxolitinib (RMML-00120886)
Cat. No.: RMML-00120886
Category: Inhibitors & Activators
INQUIRY
1 mg
5 mg
Ruxolitinib is an ATP mimic that inhibits all Janus-associated kinase. Suppresses erythroid progenitor colony formation from peripheral blood mononuclear cells of polycythemia vera patients with the constitutively active JAK2 V617F mutation. Reduces malignant cell proliferation and decreases interleukin-6 and TNF-α signaling in a JAK2 V617F-driven mouse model of myeloproliferative disorder. OTHERPromotes hair regrowth in a mouse model of alopecia areata.
Product Features
| Purity | ≥ 98% |
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| Cross Reactivity | Human, Mouse, Non-Human Primate, Other, Rat |
Compound Information
| Target Pathways | JAK/STAT |
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| CAS Number | 941678-49-5 |
| Molecular Formula | C₁₇H₁₈N₆ |
Storage & Shipping
| Handling | Refer to SDS for further information. |
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For research use only. Not for clinical use.
