Bromocriptine mesylate, D2-like dopamine receptor agonist (RMML-00120807)
Cat. No.: RMML-00120807
Category: Inhibitors & Activators
INQUIRY
500 mg
100 mg
Potent, selective D2-like dopamine receptor agonist
Product Features
| Source | Synthetic |
|---|---|
| Purity | > 99% |
| Key Features | Potent, selective D; 2; -like dopamine receptor agonist; CAS Number: 22260-51-1; Purity: > 99%; Soluble in DMSO to 100 mM and in ethanol to 25 mM (with heating); Form / State: Solid; Source: Synthetic |
Compound Information
| Target Pathways | D2-like dopamine receptor |
|---|---|
| Biological Description | Potent, selective D2-like dopamine receptor agonist (Ki values are ~8 (D2), ~5 (D3), ~290 (D4), ~440 (D1) and ~450 nM (D5)). Inhibits the release of pituitary prolactin and stimulates motor activity in Parkinson's disease. Also reverses glutamate transporter 1 (GLT-1) activity, increasing glutamate levels. |
| CAS Number | 22260-51-1 |
| Chemical Name | (5a)-2-Bromo-12'-hydroxy-2'-(1-methylethyl)-5'-(2-methylpropyl)ergotaman-3',6',18-trione methanesulfonate |
| SMILES | CS(=O)(=O)O.Brc3nc2cccc1C4=C[C@H](CN(C)[C@@H]4Cc3c12)C(=O)N[C@@]7(O[C@]6(O)N([C@@H](CC(C)C)C(=O)N5CCC[C@H]56)C7=O)C(C)C |
| Molecular Formula | C32H40BrN5O5.CH3SO3H |
| Molecular Weight | 750.70 Da |
| PubChem Identifier | 31100 |
Storage & Shipping
| Handling | Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Toxic, refer to SDS for further information. |
|---|---|
| Solubility | Soluble in DMSO to 100 mM and in ethanol to 25 mM (with heating) |
| Storage & Shipping | Store at 4°C. The product can be stored for up to 12 months. |
For research use only. Not for clinical use.
