CAY10572 (PHA-767491), Cdc7 and Cdk9 kinase inhibitor (RMML-00120750)
Cat. No.: RMML-00120750
Category: Inhibitors & Activators
INQUIRY
50 mg
10 mg
Potent dual Cdc7 and Cdk9 kinase inhibitor
Product Features
| Source | Synthetic |
|---|---|
| Purity | > 98% |
| Key Features | Potent dual Cdc7 and Cdk9 kinase inhibitor; CAS Number: 942425-68-5; Purity: > 98%; Soluble in DMSO to 10 mM; Form / State: Solid; Source: Synthetic |
Compound Information
| Target Pathways | Cdc7, Cdk9 kinase |
|---|---|
| Biological Description | Potent Cdc7 and Cdk9 kinase inhibitor (IC50 values are 10 and 34 nM for Cdc7 in the presence of 1.5 µM ATP and Cdk9 respectively). Induces apoptosis in cancer cell lines. Shows synergistic antitumor effects in vivo with 5-fluorouracil (ab142387). |
| Alternative Names | PHA-767491 |
| CAS Number | 942425-68-5 |
| Chemical Name | 2-Pyridin-4-yl-1,5,6,7-tetrahydropyrrolo[3,2-c]pyridin-4-one |
| SMILES | C1CNC(=O)C2=C1NC(=C2)C3=CC=NC=C3 |
| Molecular Weight | 213.24 Da |
| PubChem Identifier | 11715767 |
Storage & Shipping
| Handling | Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. |
|---|---|
| Solubility | Soluble in DMSO to 10 mM |
| Storage & Shipping | Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. |
For research use only. Not for clinical use.
