HA-1077 (Fasudil) (mM/mL), ROCK2 inhibitor (RMML-00120879)
Cat. No.: RMML-00120879
Category: Inhibitors & Activators
INQUIRY
20 mM/mL
ROCK2 inhibitor. 1 mL water soluble pack.
Product Features
| Source | Synthetic |
|---|---|
| Purity | > 98% |
| Key Features | ROCK2 inhibitor. 1 mL water soluble pack.; CAS Number: 103745-39-7; Purity: > 98%; Soluble in 1ml of water to give specified mM/mL concentration; Form / State: Solid; Source: Synthetic |
Compound Information
| Target Pathways | ROCK2 |
|---|---|
| Biological Description | ROCK2 inhibitor (IC50 = 1.9 µM). Also shown to inhibit PRK2 (IC50 = 4 µM), MSK1 (IC50 = 5 µM), Rsk2 (IC50 = 15 µM), PKA, p70 S6 Kinase, CaM Kinase and MLCK. Calcium antagonist and vasodilator.Soluble in 1 mL water to give specified mM/mL concentration. Find out more. |
| Alternative Names | Fasudil |
| CAS Number | 103745-39-7 |
| Chemical Name | 1-(5-Isoquinolinylsulfonyl)homopiperazine hydrochloride |
| SMILES | Cl.O=S(=O)(c2cccc1cnccc12)N3CCCNCC3 |
| Molecular Formula | C14H17N3O2S.HCl |
| Molecular Weight | 327.83 Da |
| PubChem Identifier | 163751 |
Storage & Shipping
| Handling | Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Refer to SDS for further information. |
|---|---|
| Solubility | Soluble in 1mL of water to give specified mM/mL concentration |
| Storage & Shipping | Store at room temperature. The product can be stored for up to 12 months. |
For research use only. Not for clinical use.
