Purmorphamine, Smoothened receptor agonist (RMML-00120955)
Cat. No.: RMML-00120955
Category: Inhibitors & Activators
INQUIRY
5 mg
25 mg
Smoothened receptor agonist
Product Features
| Source | Synthetic |
|---|---|
| Purity | > 98% |
| Key Features | Smoothened receptor agonist; CAS Number: 483367-10-8; Purity: > 98%; Soluble in DMSO to 10 mM; Form / State: Solid; Source: Synthetic |
Compound Information
| Target Pathways | Smoothened receptor |
|---|---|
| Biological Description | Smoothened (Smo) receptor agonist (EC50 ~ 1 μM). Induces osteogenesis in mouse mesenchymal progenitor cells . When combined with BMP-4, can transdifferentiate pre-adipocytes and myoblasts into osteoblasts. Induces differentiation of multipotent mesenchymal progenitor cells into osteoblasts. |
| CAS Number | 483367-10-8 |
| Chemical Name | 9-Cyclohexyl-N-[4-(4-morpholinyl)phenyl]-2-(1-naphthalenyloxy)-9H-purin-6-amine |
| SMILES | O1CCN(CC1)c1ccc(cc1)Nc1nc(Oc2cccc3ccccc23)nc2c1ncn2C1CCCCC1 |
| Molecular Formula | C31H32N6O2 |
| Molecular Weight | 520.63 Da |
Storage & Shipping
| Handling | Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. |
|---|---|
| Solubility | Soluble in DMSO to 10 mM |
| Storage & Shipping | Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. |
For research use only. Not for clinical use.
