Recombinant Human CNTF (RMPP-00231114)
Cat. No.: RMPP-00231114
Category: Neurotrophins
INQUIRY
5 μg
20 μg
CNTF is a potent neural factor that was originally characterized as a vital factor for the survival of chick ciliary neurons in vitro. CNTF is also important for the survival of other neural cell types, including primary sensory neurons, motor neurons, basal forebrain neurons and type 2 astrocytes. CNTF is highly conserved across species and exhibits cross-species bioactivity. Recombinant Human CNTF is synthesized as a 199 amino acid polypeptide (22.8 kDa) lacking a hydrophobic N-terminal signal for secretion.
Product Features
| Source | E.coli |
|---|---|
| Purity | ≥ 98% by SDS-PAGE gel and HPLC analyses. |
| Nature | Recombinant |
| Endotoxin Level | < 1 Eu/μg |
| Cross Reactivity | Dog, Frog, Hamster, Human, Mouse, Rat |
Protein Information
| UniProt ID | P26441 |
|---|---|
| Molecular Weight | 22.8 kDa |
| Molecular Weight Information | Predicted MW is 22856.99 Da (+/- 10 Da by ESI-TOF). Observed MW is 22858.40 Da |
| Sequence Similarities | Belongs to the CNTF family. |
| Protein Length | Full length protein |
| Cellular Localization | Cytoplasm. |
| Tissue Specificity | Nervous system. |
| Function | CNTF is a survival factor for various neuronal cell types. Seems to prevent the degeneration of motor axons after axotomy. |
Storage & Shipping
| Shipping and Storage | Shipped on Dry Ice. |
|---|
For research use only. Not for clinical use.
