Recombinant Human FGF2 Protein (Active)

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Recombinant Human FGF2 Protein (Active) (RMPP-00230636)

Cat. No.: RMPP-00230636

Category: Recombinant Protein

Research Area: Immunology

INQUIRY 100 μg 1 mg

Product Features

Source	HEK 293 cells
Purity	> 90% SDS-PAGE.
Nature	Recombinant
Endotoxin Level	≤ 1.000 Eu/µg
Animal Free	No
Tags	His tag C-Terminus
Form	Lyophilized
Applications	SDS-PAGE; Functional Studies
Key Features	Expression system: HEK 293 cells; Purity: > 90% SDS-PAGE; Endotoxin level: ≤ 1.000 Eu/µg; Active: Yes; Tags: His tag C-Terminus; Suitable for: SDS-PAGE, Functional Studies

Protein Information

UniProt ID	P15391
Molecular Weight	32 kDa including tags
Sequence	PEEPLVVKVE EGDNAVLQCL KGTSDGPTQQ LTWSRESPLK PFLKLSLGLP GLGIHMRPLA IWLFIFNVSQ QMGGFYLCQP GPPSEKAWQP GWTVNVEGSG ELFRWNVSDL GGLGCGLKNR SSEGPSSPSG KLMSPKLYVW AKDRPEIWEG EPPCLPPRDS LNQSLSQDLT MAPGSTLWLS CGVPPDSVSR GPLSWTHVHP KGPKSLLSLE LKDDRPARDM WVMETGLLLP RATAQDAGKY YCHRGNLTMS FHLEITARPV LWHWLLRTGG WK
Sequence Similarities	Contains 2 Ig-like C2-type (immunoglobulin-like) domains.
Protein Length	Protein fragment
Cellular Localization	Membrane.
Function	Assembles with the antigen receptor of B lymphocytes in order to decrease the threshold for antigen receptor-dependent stimulation.
Involvement in Disease	Defects in CD19 are the cause of immunodeficiency common variable type 3 (CVID3); also called antibody deficiency due to CD19 defect. CVID3 is a primary immunodeficiency characterized by antibody deficiency, hypogammaglobulinemia, recurrent bacterial infections and an inability to mount an antibody response to antigen. The defect results from a failure of B-cell differentiation and impaired secretion of immunoglobulins; the numbers of circulating B cells is usually in the normal range, but can be low.
Post-translational Modifications	Phosphorylated on serine and threonine upon DNA damage, probably by ATM or ATR. Phosphorylated on tyrosine following B-cell activation.

Storage & Shipping

Shipping and Storage	Shipped at 4°C. Store at 4°C (stable for up to 12 months). Store at -20°C or -80°C. Avoid freeze / thaw cycle. For long term storage it is recommended to add a carrier protein on reconstitution (0.1% HSA or BSA). Working aliquots stored with a carrier protein are stable for at least 3 months at -20°C to -80°C.. pH: 7.40Constituents: 5% Trehalose, PBSLyophilized from 0.22 µm filtered solution. This product is an active protein and may elicit a biological response in vivo, handle with caution.

Shipping and Storage

Shipped at 4°C. Store at 4°C (stable for up to 12 months). Store at -20°C or -80°C. Avoid freeze / thaw cycle. For long term storage it is recommended to add a carrier protein on reconstitution (0.1% HSA or BSA). Working aliquots stored with a carrier protein are stable for at least 3 months at -20°C to -80°C..
pH: 7.40Constituents: 5% Trehalose, PBSLyophilized from 0.22 µm filtered solution.
This product is an active protein and may elicit a biological response in vivo, handle with caution.

For research use only. Not for clinical use.