Recombinant Human IL-12 p70 (CHO derived) (RMPP-00231287)
Cat. No.: RMPP-00231287
Category: Growth Factors & Cytokines
INQUIRY
2 μg
10 μg
IL-12 is a potent regulator of cell-mediated immune responses and it induces IFN-γ production by NK and T cells. It is produced by activated monocytes/macrophage cells, B lymphocytes and connective tissue-type mast cells. Among its biological activities, IL-12 promotes the growth and activity of activated NK, CD4+ and CD8+ cells, and induces the development of IFN-γ-producing Th1 cells. Recombinant Human IL-12 is a 75.0 kDa heterodimeric glycoprotein consisting of disulfide-linked 35 kDa (p35) and 40 kDa (p40) subunits (503 total amino acid residues).
Product Features
| Source | CHO cells |
|---|---|
| Purity | ≥ 98% by SDS-PAGE gel and HPLC analyses. |
| Nature | Recombinant |
| Endotoxin Level | < 1 Eu/μg |
| Cross Reactivity | Bacteria, Human, Human + Hamster, Human + Mouse, Monkey, Mouse |
Protein Information
| UniProt ID | p35: P29459 p40: P29460 |
|---|---|
| Molecular Weight | 75 kDa |
Storage & Shipping
| Shipping and Storage | Shipped on Dry Ice. |
|---|
For research use only. Not for clinical use.