Recombinant Human IL-5 (RMPP-00231335)
Cat. No.: RMPP-00231335
Category: Growth Factors & Cytokines
INQUIRY
2 μg
10 μg
IL-5 is a hematopoietic growth factor that stimulates the proliferation and activation of eosinophils. Produced by mast cells, T cells, and eosinophils, IL-5 plays an important role in inducing cell-mediated immunity against parasitic infections and certain tumors. Elevated levels of IL-5 lead to Eosinophilia, which may result in the induction of asthma and other allergic diseases. Human and murine IL-5 is cross-species reactive. Recombinant Human IL-5 is a 26.5 kDa disulfide-linked homodimeric protein containing two 116 amino acid chains.
Product Features
| Source | E.coli |
|---|---|
| Purity | ≥ 98% by SDS-PAGE gel and HPLC analyses. |
| Nature | Recombinant |
| Endotoxin Level | < 1 Eu/μg |
| Cross Reactivity | Guinea Pig, Human, Monkey, Mouse |
Protein Information
| UniProt ID | P05113 |
|---|---|
| Molecular Weight | 26.5 kDa |
| Sequence Similarities | Belongs to the IL-5 family. |
| Protein Length | Full length protein |
| Cellular Localization | Secreted. |
| Function | Factor that induces terminal differentiation of late-developing B-cells to immunoglobulin secreting cells. |
Storage & Shipping
| Shipping and Storage | Shipped on Dry Ice. |
|---|
For research use only. Not for clinical use.
